Launch of a transport manned spacecraft to the ISS on December 8, 2021. During the flight of the spacecraft, controlled by cosmonaut Alexander Misurkin, two Japanese space tourists, members of the 20th ISS visiting expedition, were delivered to the ISS. On December 20, 2021, the crew returned to Earth. This flight was the last for Alexander Misurkin: on March 31, 2022, Misurkin completed his activities in the Roscosmos cosmonaut corps.